Kangyi Zhang 张康毅

Engineer

In the 2009 movie ‘G.I. Joe: The Rise of Cobra’, a form of microscopic robot, known as ‘nano-mites’, was hailed as an ultimate devastating device capable of devouring a tank in seconds. In another media-driven hype on nanotechnology, Apple has been rolling out newer generations of Ipod Nano. In this case, the term nano is merely used to emphasize the miniature size of the system.

 

Nanotechnology involves length scale in the range of 1 to 100nm, although the definition is never strictly adhered. Why is there so much interest in these infinitesimal objects?


Think about pants that stay dirt-free! Stain-resistant fabrics that repel oil and water due to nanoscale whisker features have been developed. Tennis rackets and bikes made of carbon nanotubes are stronger than steel and much lighter. Can bullet-proof vest be as light as normal clothing? Nanoparticle-liquid mixture is usually liquid and turns solid when a bullet or sharp knife penetrates it.

http://www.nanooze.org/english/article_listings_dailylife.html


For cancer patients, non-specific chemotherapy and radiotherapy result in the death of healthy cells whilst removing the tumors. Using nanoparticles attached with recognition molecules, drugs can be specifically delivered to the tumors, without affecting healthy cells. In the realm of tissue engineering, nanotopography can be used to control the fate of stem cells. Stem cells exposed to different nano-features will differentiate into a specific lineage. Hence, this consideration is critical when regenerating tissues or growing whole organs. Tissue engineering is a solution to the perpetual shortage in organ donors.

 

For more applications of nanotechnology:

http://en.wikipedia.org/wiki/List_of_nanotechnology_applications


Kangyi graduated magna cum laude from Brown University with an honors degree in Biomedical Engineering in 2009. He obtained his Masters of Science from Northwestern University in 2012.

http://www.n-base.org/

 

Research Interest: Oral Cancer, Tissue Engineering, Drug Delivery, Biomaterials, Nanoparticles, Nanodiamonds


List of Publications


Engineering Nanoparticulate Diamond for  Applications in Nanomedicine and Biology

 

Man HB, Zhang K, Robinson E, Chow EK, Ho D
Chapter 15, Ultrananocrystalline Diamond, 2nd Edition 2012 Elsevier




Characterization of membrane materials and membrane coatings for bioreactor units of bioartificial kidneys

Ni MTeo JCIbrahim MSZhang KTasnim FChow PYZink D, Ying JY.

Biomaterials. 2011 Feb;32(6):1465-76

Conferences

Nanodiamond therapeutic delivery vehicles for cancer treatment and regenerative medicine

Zhang K, Kim HJ, Gatica M, Moore L, Chow EK, Ho D
International Association for Dental Research (20-23th Mar 2013) Seattle WA




Awards and Honorary Societies

2007

Agency for Science Technology and Research (Singapore)

Chairman’s Honors List 2007

2008

Undergraduate Teaching Research Award (Brown University)

2008

Agency for Science Technology and Research (Singapore)

Chairman’s Honors List 2008

2008

Tau Beta Pi Engineering Honor Society (Alpha of Rhode Island)

2009

Sigma Xi Scientific Research Society (Brown University Chapter)

2009

Phi Beta Kappa (Rhode Island Alpha)

2009

American Chemistry Society

2009

Agency for Science Technology and Research (Singapore)

Chairman’s Honors List 2009

 


Dean Ho (first on the left) and his illustrious lab members.
Waitress not included.
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